Research Projects commissioned









 

  Please note: 

Copies of the final report are freely available for those projects where the 'total cost' is provided.  To receive a copy, please contact us giving details of the project or projects in which you are interested and your full postal address.


PRIORITY AREA A: Ways of effecting, maintaining and evaluating behavioural changes leading to a reduction in smoking at all ages, particularly children


The Tobacco Addiction Collaborative Review Group of the Cochrane Collaboration (Project ref: NCP/ICV/055/A)
Dr Tim Lancaster, University of Oxford
Completed: 31 August 1998 Total cost: 71,579


PRIORITY AREA B: The organisation and evaluation of services, including medical, psychosocial, counselling and other services, to meet the needs of those found to be at high risk of cancer due to a genetic susceptibility


Investigation of the prevalence of germline mutations in BRCA1 and BRCA2 in women with breast cancer diagnosed before thirty years of age or with a strong family history (Project ref: NCP/B11/34)
Dr Shirley Hodgson, United Medical and Dental Schools of Guy's and St. Thomas' Hospitals
Completed: 30 September 1998 Total cost: 120,546
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A population based study of familial breast cancer in East Anglia (Project ref: NCP/B15)
Professor Bruce Ponder, University of Cambridge
Completed: 2 February 2000 Total cost: 205,743


Evaluating services for women with familial risk of breast cancer; consumer push or practitioner pull in primary care consultations?   (Project ref: NCP/B22c)
Professor Ann-Louise Kinmonth, University of Cambridge
Completed: 31 August 2000 Total cost: 65,989


Public understanding of cancer genetics - assessing knowledge and attitudes to inform policy for testing (Project ref: NCP/B32)
Professor Deborah Sharp, University of Bristol
Completed: 16 May 2000  Total cost: 111,092


A descriptive study of cancer genetics services (Project ref: NCP/B42)
Professor Klim McPherson/Dr Penny Hopwood, London School of Hygiene & Tropical Medicine
Completed: 13 April 2001   Total cost: 214,021


PRIORITY AREA C: Factors influencing delayed presentation by patients (e.g. psychosocial) and variations in onward referrals by physicians to oncology specialists


Breast cancer in British native and South Asian women: presentation, referral and survival (Project ref: NCP/C03)
Dr Isabel dos Santos Silva, London School of Hygiene and Tropical Medicine
Completed: 28 February 1997 Total cost: 45,889


Systematic review of patient-mediated delay in presentation of cancer and provider-mediated delay and variation in onward referral for treatment (Project ref: NCP/ICV/012/C)
Professor Amanda Ramirez, United Medical and Dental Schools of Guy's and St. Thomas' Hospitals
Completed: 31 March 1998 Total cost: 41,003


PRIORITY AREA D: Factors influencing the accrual of patients into cancer trials (including why clinicians are reluctant to enter patients into national multicentre trials)


Factors influencing the accrual of patients into clinical trials: An examination of the BASO II trial for the treatment of well-differentiated small, node negative carcinomas of the breast (Project ref: NCP/D01)
Professor Roger Blamey, The University of Nottingham
Completed: 30 April 1999 Total cost: 121,223


Using a consumers' advisory group to increase accrual into trials (Project ref: NCP/D18)
Miss Joanne Marsden, The Institute of Cancer Research
Completed: 31 October 1996 Total cost: 28,549


UKCCCR Register of UK Cancer Trials (Project ref: NCP/D20)
Dr Lesley Stewart, MRC Cancer Trials Office
Completed: 30 September 2000 Total cost: 54,101


Improving communication during recruitment to clinical trials of cancer therapy (Project ref: NCP/D21)
Professor Lesley Fallowfield, University College London
Completed: 3 August 2000 Total cost: 194,991


Systematic review of factors influencing the accrual of patients into cancer trials (including why clinicians are reluctant to participate in national multicentre trials)   (Project ref: NCP/ICV/022/D)
Mrs Linda Ward, University of Birmingham
Completed: 31 January 1998 Total cost: 33,942


PRIORITY AREA E: Studies designed to explain variations in disease outcomes, particularly in relation to variations in patterns of practice


Variation in survival in cancers of the stomach, pancreas and oesophagus (Project ref: NCP/E01)
Dr Max Bachmann, University of Bristol
Completed: 30 April 1999 Total cost: 284,061


Population based study of patterns of care and survival for bone sarcoma (Project ref: NCP/E16)
Mr Charles Stiller, University of Oxford
Completed: 30 September 2000 Total cost: 103,122


Cancer treatment policies, delay in referral and their effect on survival (Project ref: NCP/E32)
Professor David Forman, University of Leeds
Completed: 29 February 2000 Estimated cost: 307,343


Review of studies designed to explain variation in disease outcome, particularly in relation to variations in patterns of practice (Project ref: NCP/ICV/045/E)
Dr Derek Pheby, University of the West of England
Completed: 31 October 1997 Total cost: 23,715


PRIORITY AREA F: Comparison of care for common cancers (e.g. lung, breast, colorectal) in specialist and non-specialist treatment settings with respect to psychosocial and clinical outcomes; and the relative costs of managing each step of disease progression


Management of lung cancer: A comparison of management strategies, outcomes and resource utilisation in specialist and non-specialist centres (Project ref: NCP/F02)
Dr Ann Cull, Western General Hospital NHS Trust, Edinburgh
Completed: 31 March 1999 Estimated cost: 231,970


A randomised controlled trial comparing the effectiveness of rapid diagnosis clinics and best alternative care (Project ref: NCP/F03)
Dr Paola Dey, University of Manchester
Completed: 28 February 1998 Total cost: 49,598


Systematic review of the evidence relating process of care to outcome and cost in specialist and non-specialist hospital settings (Project ref: NCP/ICV/028/F)
Dr Maggie Harding, St. George's Hospital Medical School
Completed: 31 March 1997 Total cost: 15,048


PRIORITY AREA G: The clinical utility of second-line chemotherapy in advanced common cancers, particularly its comparison to best supportive care


Appropriate management for patients with advanced breast cancer (Project ref: NCP/G01)
Professor Michael Richards, United Medical and Dental Schools of Guy's and St. Thomas' Hospitals
Completed: 31 March 2002 Estimated cost: 343,619


Chemotherapy for patients with non-small cell lung cancer (NSCLC): estimating the costs of extended use of chemotherapy for this group of patients (Project ref: NCP/G04)
Professor John Posnett, York Health Economics Consortium, University of York
Completed: 31 December 2000 Total cost: 39,521


The patient's perspective of the clinical utility of second-line chemotherapy (Project ref: NCP/G12)
Dr Richard Osborne, Poole Hospital NHS Trust
Completed: 30 June 1998 Estimated cost: 41,610


PRIORITY AREA I: Optimal management strategies for unrelieved symptoms, including pain and non-pain, in cancer patients


Bibliography and systematic reviews in cancer pain management (Project ref: NCP/ICV/I03)
Dr Henry McQuay, University of Oxford
Completed: 30 September 1997 Total cost: 27,379


Hormone replacement therapy in advanced breast cancer (Project ref: NCP/I14)
Professor Jack Cuzick, Imperial Cancer Research Fund
Completed: 30 September 1997 Total cost: 30,765


Systematic review of the management of constipation in cancer patients (Project ref: NCP2/I210)
Dr Ian Penman, University of Edinburgh
Completed: 31 December 1999 Estimated cost: 87,349


Systematic review of the management of intestinal obstruction due to advanced gynaecological and gastrointestinal cancer (Project ref: NCP2/I211)
Dr Karen Broadley, Royal Marsden NHS Trust
Completed: 5 October 1998 Total cost: 35,297


PRIORITY AREA J: The most appropriate and cost effective model of service delivery and level of provision of palliative care services, including the role of Nurse Practitioners


Impact of an hospital-based palliative care service in the community (Project ref: NCP/J01)
Professor Geoffrey Hanks, University of Bristol
Completed: 4 August 2000 Total cost: 245,588


Appropriate and cost effective models of service delivery (Project ref: NCP/ICV/016/J)
Professor Nick Bosanquet, Imperial College of Science, Technology and Medicine
Completed: 31 July 1997 Total cost: 46,767


Development and evaluation of Nurse Practitioner follow-up in the management of patients with lung cancer (Project ref: NCP/J17/18)
Professor Jessica Corner, The Institute of Cancer Research
Completed: 31 August 2000 Total cost: 252,487


PRIORITY AREA K: The early natural history of cancers that may particularly lend themselves to screening to reduce mortality (e.g. prostate, oral and skin cancers)


A systematic review of the early natural history of prostate, skin and oral cancers (Project ref: NCP/ICV/042/K)
Dr Sue Moss, The Institute of Cancer Research
Completed: 31 March 1997 Total cost: 47,788


PRIORITY AREA Q: The most cost-effective way to provide information to meet the needs of cancer patients, their families, health care professionals and the public


Evaluation of video-taped information in cancer genetic counselling (Project ref: NCP/Q24)
Dr Ann Cull, Edinburgh Healthcare NHS Trust
Completed: 31 March 1997 Total cost: 35,205


Systematic reviews of the effectiveness of different ways of meeting the information needs of people with cancer (Project ref: NCP2/Q232)
Professor Ian Watt, University of York
Completed: 30 September 1999    Total cost: 81,531


PRIORITY AREA R: The psychosocial consequences for patients who have increased participation in clinical decision making


A randomised controlled trial of cytological surveillance versus patient choice between surveillance and colposcopy in managing mildly abnormal cervical smears (Project ref: NCP2/R207)
Professor Henry Kitchener, University of Manchester
Completed: 31 July 2000    Total  cost: 101,760


PRIORITY AREA U: The roles of adjuvant, neo-adjuvant and combined modality treatments for primary common cancers


Post-operative radiotherapy in non-small cell lung cancer: A Systematic Review and meta-analysis of individual patient data from nine randomised trials (Project ref: NCP/U03)
Dr Lesley Stewart, MRC Cancer Trials Office
Completed: 30 June 1998 Total cost: 46,461


A very large scale trial of chemotherapy for all stages of non-small cell lung cancer (NSCLC)   (Project ref: NCP/U05)
Professor Stephen Spiro, University College London
Completed: 30 November 2001 Total cost: 314,539


Cytological assessment of prognosis and response to neoadjuvant and adjuvant chemotherapy in breast cancer (Project ref: NCP/U15)
Dr Trevor Powles, The Royal Marsden NHS Trust
Completed: 30 September 1996 Total cost: 4,692


Biochemical markers of response to adjuvant tamoxifen therapy in breast cancer (Project ref: NCP/U16)
Professor Mitchell Dowsett, The Institute of Cancer Research
Completed: 30 September 1998 Total cost: 157,390


PRIORITY AREA V: Cancer treatment of the elderly including clinical outcomes and cost effectiveness


A study of treatment decisions in elderly patients with colorectal cancer and their consequences on multi-dimensional aspects of patient functioning (Project ref: NCP/V19)
Professor Jessica Corner, The Institute of Cancer Research
Completed: 31 December 1999 Total cost: 265,777


Systematic reviews of: a) surgery for colorectal cancer in elderly patients; and b) palliative chemotherapy for advanced or metastatic colorectal cancer (Project ref: NCP2/V207)
Dr Peter Simmonds, University of Southampton
Completed: 31 March 1999 Total cost: 51,807


PRIORITY AREA W: The value of integrating quality of life data and data on costs in the measurements of outcome in prevention, treatment and care of cancer patients and their carers


Measurement of quality of life in advanced ovarian cancer - can we keep it simple?   (Project ref: NCP/W07)
Mrs Maxine Stead, Yorkshire Cancer Organisation, University of Leeds
Completed: 31 August 1999 Total cost: 50,966


Automated screening and recording of quality of life data (Project ref: NCP/W13)
Professor Peter Selby, University of Leeds
Completed: 2 September 1999 Total cost: 324,150


Determining sample sizes for cancer trials involving quality of life instruments (Project ref: NCP/W16)
Professor Michael Campbell, University of Southampton
Completed: 5 December 1996 Total cost: 34,720
             


PRIORITY AREA X: Comparison of the cost effectiveness of different psychosocial interventions including complementary therapies and voluntary groups for patients and their families


A feasibility study to assess the efficacy of bilingual health advocacy in ethnic minority cancer patients (Project ref: NCP2/X215)
Dr Nicky Thomas, King's College London
Completed: 30 June 2000 Total cost: 62,149


A brief multifaceted nurse-delivered intervention for comorbid major depressive disorder in outpatients with advanced and recurrent cancer: a pilot evaluation (Project ref: NCP2/X216)
Dr Michael Sharpe, University of Edinburgh
Completed: 31 August 2001 Total cost: 192,184


A randomised controlled study of the effects of reflexology on quality of life (including mood, adjustment, function, coping and patient satisfaction) in patients with early breast cancer (Project ref: NCP2/X229)
Professor Leslie Walker, University of Hull
Start date: 2 April 2002  End date: 1 April 2005 Total cost: 129,938


PRIORITY AREA Y: What prevents terminally ill people from dying at home, if they so wish, and how can general practitioners and their teams access information to help them care more effectively for their patients at home?


Which cancer patients die at home?: the effects of social deprivation and patient characteristics in England (Project ref: NCP/Y04)
Professor Irene Higginson, Kings College London
Completed: 28 February 1997 Total cost: 48,057


Meeting the needs of cancer patients who wish to remain at home until they die: A systematic review of preferences, problems and cost-effective solutions (Project ref: NCP/ICV/014/Y)
Professor Irene Higginson, Kings College London
Completed: 31 March 1997 Total cost: 31,192


  Please note: 

Copies of the final report are freely available for those projects where the 'total cost' is provided.  To receive a copy, please contact us giving details of the project or projects in which you are interested and your full postal address.

 


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Last updated 06 June 2008
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