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Project Summary and Objectives: Constipation is a common and often distressing symptom in cancer patients. There are several different candidate mechanisms, including the use of opiates; complications such as faecal impaction may require in-patient treatment; side-effects of drugs may also be significant; potentially valuable new approaches to management of constipation have recently been developed and evaluated, including polyethylene (PEG) based agents, and suppositories. The aim of this project is to prepare a systematic review of clinical trials of the treatment of constipation in cancer patients, based on the medical and nursing literature, and on unpublished data (e.g. from pharmaceutical companies). Further information can be obtained from: Dr Ian Penman Consultant Gastroenterologist Western General Hospitals NHS Trust Western General Hospital Crewe Road Edinburgh EH4 2XU UK Tel: 0131 537 1758 Fax: 0131 537 1007 |
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