Richards Group

Living Systems Institute, University of Exeter

Current collaborators include:

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Most recent publications:

  • Cockerell A, Wright L, Dattani A, Guo G, Smith A, Tsaneva-Atanasova K, Richards DM: Biophysical models of early mammalian embryogenesis. Stem Cell Rep 18:26 (Stem Cell Reports)
  • Carmichael RE, Richards DM, Fahimi HD, Schrader M: Organelle Membrane Extensions in Mammalian Cells. Biology (Basel) 12(5):664 (PubMed)
  • Hembrow J, Deeks MJ, Richards DM: Automatic extraction of actin networks in plants. PLoS Comput Biol 19(8):e1011407 (PLoS Computational Biology)
  • Giuraniuc CV, ..., Richards DM, ..., Brand AC: Dynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicans. Accepted in mBio (Preprint on bioRxiv)
  • Richards DM: Receptor models of phagocytosis: the effect of target shape. Adv Exp Med Biol 1246:55-70 (PubMed)
  • Richards DM, Walker JJ, Tabak J: Ion channel noise shapes the electrical activity of endocrine cells. PLoS Comput Biol 16(4):e1007769 (PubMed)
  • Passmore JB, ..., Richards DM, ..., Schrader M: Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation. Biochim Biophys Acta Mol Cell Res (PubMed)
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We are grateful for funding from:

Phagocytosis is the fascinating process by which our immune cells engulf and destroy foreign particles. How easily such cells can destroy a foreign particle depends crucially on the particle shape and size, and the direction that the cell meets the particle. This is directly relevant to the design of microparticle drug delivery systems (tiny particles that can be used to carry drugs) since such particles must be carefully designed to avoid removal via phagocytosis. Click below for a gentle introduction to these topics and how our work is helping.

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Contact information and links

Address: Living Systems Institute, University of Exeter, Exeter EX4 4SB, UK


Phone: +44 (0)1392 727483

YouTube: David Richards Group

Twitter: Richards Group

Networks: Exeter Health Analytics (EHA) network