Research
Projects commissioned
Please note:
Copies of the final report are freely available for those projects where the 'total cost' is provided. To receive a copy, please contact us giving details of the project or projects in which you are interested and your full postal address.
PRIORITY AREA A: Ways of effecting, maintaining and evaluating behavioural changes leading to a reduction in smoking at all ages, particularly children
The
Tobacco Addiction Collaborative Review Group of the Cochrane Collaboration
(Project ref: NCP/ICV/055/A)
Dr Tim Lancaster, University of
Oxford
Completed: 31 August 1998
Total
cost: £71,579
PRIORITY AREA B: The organisation and evaluation of services, including medical, psychosocial, counselling and other services, to meet the needs of those found to be at high risk of cancer due to a genetic susceptibility
Investigation
of the prevalence of germline mutations in BRCA1 and BRCA2 in women with
breast cancer diagnosed before thirty years of age or with a strong family
history (Project ref: NCP/B11/34)
Dr Shirley Hodgson, United Medical and Dental Schools of Guy's and
St. Thomas' Hospitals
Completed: 30 September 1998
Total
cost: £120,546
Download
executive summary (31 KB)
A
population based study of familial breast cancer in East Anglia (Project
ref: NCP/B15)
Professor Bruce Ponder, University of Cambridge
Completed: 2 February 2000
Total
cost: £205,743
Evaluating
services for women with familial risk of breast cancer; consumer push or
practitioner pull in primary care consultations? (Project ref:
NCP/B22c)
Professor Ann-Louise Kinmonth, University of Cambridge
Completed: 31 August 2000
Total
cost: £65,989
Public
understanding of cancer genetics - assessing knowledge and attitudes to
inform policy for testing (Project ref: NCP/B32)
Professor Deborah Sharp, University of Bristol
Completed: 16 May 2000
Total
cost: £111,092
A
descriptive study of cancer genetics services (Project ref: NCP/B42)
Professor Klim McPherson/Dr Penny Hopwood, London School of Hygiene
& Tropical Medicine
Completed: 13 April 2001 Total
cost: £214,021
PRIORITY AREA C: Factors influencing delayed presentation by patients (e.g. psychosocial) and variations in onward referrals by physicians to oncology specialists
Breast
cancer in British native and South Asian women: presentation, referral and
survival (Project ref: NCP/C03)
Dr Isabel dos Santos Silva, London School of Hygiene and Tropical
Medicine
Completed: 28 February 1997
Total
cost: £45,889
Systematic
review of patient-mediated delay in presentation of cancer and
provider-mediated delay and variation in onward referral for treatment
(Project ref: NCP/ICV/012/C)
Professor Amanda Ramirez, United Medical and Dental Schools of Guy's
and St. Thomas' Hospitals
Completed: 31 March 1998
Total
cost: £41,003
PRIORITY AREA D: Factors influencing the accrual of patients into cancer trials (including why clinicians are reluctant to enter patients into national multicentre trials)
Factors
influencing the accrual of patients into clinical trials: An examination
of the BASO II trial for the treatment of well-differentiated small, node
negative carcinomas of the breast (Project ref: NCP/D01)
Professor Roger Blamey, The University of Nottingham
Completed: 30 April 1999
Total
cost: £121,223
Using
a consumers' advisory group to increase accrual into trials (Project ref:
NCP/D18)
Miss Joanne Marsden, The Institute of Cancer Research
Completed: 31 October 1996
Total
cost: £28,549
UKCCCR
Register of UK Cancer Trials (Project ref: NCP/D20)
Dr Lesley Stewart, MRC Cancer Trials Office
Completed: 30 September 2000
Total
cost: £54,101
Improving
communication during recruitment to clinical trials of cancer therapy
(Project ref: NCP/D21)
Professor Lesley Fallowfield, University College London
Completed: 3 August 2000
Total
cost: £194,991
Systematic
review of factors influencing the accrual of patients into cancer trials
(including why clinicians are reluctant to participate in national
multicentre trials) (Project ref: NCP/ICV/022/D)
Mrs Linda Ward, University of Birmingham
Completed: 31 January 1998
Total
cost: £33,942
PRIORITY AREA E: Studies designed to explain variations in disease outcomes, particularly in relation to variations in patterns of practice
Variation
in survival in cancers of the stomach, pancreas and oesophagus (Project
ref: NCP/E01)
Dr Max Bachmann, University of Bristol
Completed: 30 April 1999
Total
cost: £284,061
Population
based study of patterns of care and survival for bone sarcoma (Project ref: NCP/E16)
Mr Charles Stiller, University of Oxford
Completed: 30 September 2000 Total
cost: £103,122
Cancer
treatment policies, delay in referral and their effect on survival
(Project ref: NCP/E32)
Professor David Forman, University of Leeds
Completed: 29 February 2000
Estimated
cost: £307,343
Review
of studies designed to explain variation in disease outcome, particularly
in relation to variations in patterns of practice (Project ref: NCP/ICV/045/E)
Dr Derek Pheby, University of the West of England
Completed: 31 October 1997
Total
cost: £23,715
PRIORITY AREA F: Comparison of care for common cancers (e.g. lung, breast, colorectal) in specialist and non-specialist treatment settings with respect to psychosocial and clinical outcomes; and the relative costs of managing each step of disease progression
Management
of lung cancer: A comparison of management strategies, outcomes and
resource utilisation in specialist and non-specialist centres (Project
ref: NCP/F02)
Dr Ann Cull, Western General Hospital NHS Trust, Edinburgh
Completed: 31 March 1999
Estimated cost:
£231,970
A
randomised controlled trial comparing the effectiveness of rapid diagnosis
clinics and best alternative care (Project ref: NCP/F03)
Dr Paola Dey, University of Manchester
Completed: 28 February 1998
Total
cost: £49,598
Systematic
review of the evidence relating process of care to outcome and cost in
specialist and non-specialist hospital settings (Project ref: NCP/ICV/028/F)
Dr Maggie Harding, St. George's Hospital Medical School
Completed: 31 March 1997
Total
cost: £15,048
PRIORITY AREA G: The clinical utility of second-line chemotherapy in advanced common cancers, particularly its comparison to best supportive care
Appropriate
management for patients with advanced breast cancer (Project ref: NCP/G01)
Professor Michael Richards, United Medical and Dental Schools of
Guy's and St. Thomas' Hospitals
Completed: 31 March 2002
Estimated
cost: £343,619
Chemotherapy
for patients with non-small cell lung cancer (NSCLC): estimating the costs
of extended use of chemotherapy for this group of patients (Project ref:
NCP/G04)
Professor John Posnett, York Health Economics Consortium, University
of York
Completed: 31 December 2000
Total
cost: £39,521
The
patient's perspective of the clinical utility of second-line chemotherapy
(Project ref: NCP/G12)
Dr Richard Osborne, Poole Hospital NHS Trust
Completed: 30 June 1998 Estimated
cost: £41,610
PRIORITY AREA I: Optimal management strategies for unrelieved symptoms, including pain and non-pain, in cancer patients
Bibliography
and systematic reviews in cancer pain management (Project ref: NCP/ICV/I03)
Dr Henry McQuay, University of Oxford
Completed: 30 September 1997
Total
cost: £27,379
Hormone
replacement therapy in advanced breast cancer (Project ref: NCP/I14)
Professor Jack Cuzick, Imperial Cancer Research Fund
Completed: 30 September 1997
Total
cost: £30,765
Systematic
review of the management of constipation in cancer patients (Project ref:
NCP2/I210)
Dr Ian Penman, University of Edinburgh
Completed: 31 December 1999
Estimated
cost: £87,349
Systematic
review of the management of intestinal obstruction due to advanced
gynaecological and gastrointestinal cancer (Project ref: NCP2/I211)
Dr Karen Broadley, Royal Marsden NHS Trust
Completed: 5 October 1998
Total
cost: £35,297
PRIORITY AREA J: The most appropriate and cost effective model of service delivery and level of provision of palliative care services, including the role of Nurse Practitioners
Impact
of an hospital-based palliative care service in the community (Project
ref: NCP/J01)
Professor Geoffrey Hanks, University of Bristol
Completed: 4 August 2000
Total
cost: £245,588
Appropriate
and cost effective models of service delivery (Project ref: NCP/ICV/016/J)
Professor Nick Bosanquet, Imperial College of Science, Technology and
Medicine
Completed: 31 July 1997 Total
cost: £46,767
Development
and evaluation of Nurse Practitioner follow-up in the management of
patients with lung cancer (Project ref: NCP/J17/18)
Professor Jessica Corner, The Institute of Cancer Research
Completed: 31 August 2000
Total
cost: £252,487
PRIORITY AREA K: The early natural history of cancers that may particularly lend themselves to screening to reduce mortality (e.g. prostate, oral and skin cancers)
A
systematic review of the early natural history of prostate, skin and oral
cancers (Project ref: NCP/ICV/042/K)
Dr Sue Moss, The Institute of Cancer Research
Completed: 31 March 1997
Total
cost: £47,788
PRIORITY AREA Q: The most cost-effective way to provide information to meet the needs of cancer patients, their families, health care professionals and the public
Evaluation
of video-taped information in cancer genetic counselling (Project ref: NCP/Q24)
Dr Ann Cull, Edinburgh Healthcare NHS Trust
Completed: 31 March 1997
Total
cost:
£35,205
Systematic
reviews of the effectiveness of different ways of meeting the information
needs of people with cancer (Project ref: NCP2/Q232)
Professor Ian Watt, University of York
Completed: 30 September 1999 Total cost: £81,531
PRIORITY AREA R: The psychosocial consequences for patients who have increased participation in clinical decision making
A
randomised controlled trial of cytological surveillance versus patient
choice between surveillance and colposcopy in managing mildly abnormal
cervical smears (Project ref: NCP2/R207)
Professor Henry Kitchener, University of Manchester
Completed: 31 July 2000 Total cost: £101,760
PRIORITY AREA U: The roles of adjuvant, neo-adjuvant and combined modality treatments for primary common cancers
Post-operative
radiotherapy in non-small cell lung cancer: A Systematic Review and
meta-analysis of individual patient data from nine randomised trials
(Project ref: NCP/U03)
Dr Lesley Stewart, MRC Cancer Trials Office
Completed: 30 June 1998 Total
cost: £46,461
A
very large scale trial of chemotherapy for all stages of non-small cell
lung cancer (NSCLC) (Project ref: NCP/U05)
Professor Stephen Spiro, University College London
Completed: 30 November 2001
Total cost: £314,539
Cytological
assessment of prognosis and response to neoadjuvant and adjuvant
chemotherapy in breast cancer (Project ref: NCP/U15)
Dr Trevor Powles, The Royal Marsden NHS Trust
Completed: 30 September 1996
Total
cost: £4,692
Biochemical
markers of response to adjuvant tamoxifen therapy in breast cancer
(Project ref: NCP/U16)
Professor Mitchell Dowsett, The Institute of Cancer Research
Completed: 30 September 1998
Total
cost: £157,390
PRIORITY AREA V: Cancer treatment of the elderly including clinical outcomes and cost effectiveness
A
study of treatment decisions in elderly patients with colorectal cancer
and their consequences on multi-dimensional aspects of patient functioning
(Project ref: NCP/V19)
Professor Jessica Corner, The Institute of Cancer Research
Completed: 31 December 1999
Total
cost: £265,777
Systematic reviews of:
a) surgery for colorectal cancer in elderly patients; and b) palliative
chemotherapy for advanced or metastatic colorectal cancer (Project ref:
NCP2/V207)
Dr Peter Simmonds, University of Southampton
Completed: 31 March 1999
Total
cost: £51,807
PRIORITY AREA W: The value of integrating quality of life data and data on costs in the measurements of outcome in prevention, treatment and care of cancer patients and their carers
Measurement
of quality of life in advanced ovarian cancer - can we keep it simple?
(Project ref: NCP/W07)
Mrs Maxine Stead, Yorkshire Cancer Organisation, University of
Leeds
Completed: 31 August 1999
Total
cost: £50,966
Automated
screening and recording of quality of life data (Project ref: NCP/W13)
Professor Peter Selby, University of Leeds
Completed: 2 September 1999
Total
cost: £324,150
Determining
sample sizes for cancer trials involving quality of life instruments
(Project ref: NCP/W16)
Professor Michael Campbell, University of Southampton
Completed: 5 December 1996
Total
cost: £34,720
PRIORITY AREA X: Comparison of the cost effectiveness of different psychosocial interventions including complementary therapies and voluntary groups for patients and their families
A
feasibility study to assess the efficacy of bilingual health advocacy in
ethnic minority cancer patients (Project ref: NCP2/X215)
Dr Nicky Thomas, King's College London
Completed: 30 June 2000 Total
cost: £62,149
A
brief multifaceted nurse-delivered intervention for comorbid major
depressive disorder in outpatients with advanced and recurrent cancer: a
pilot evaluation (Project ref: NCP2/X216)
Dr Michael Sharpe, University of Edinburgh
Completed: 31 August 2001
Total cost: £192,184
A randomised controlled study of
the effects of reflexology on quality of life (including mood, adjustment,
function, coping and
patient satisfaction) in patients with early breast cancer (Project ref: NCP2/X229)
Professor Leslie Walker, University of Hull
Start date: 2 April 2002 End date:
1 April 2005 Total cost:
£129,938
PRIORITY AREA Y: What prevents terminally ill people from dying at home, if they so wish, and how can general practitioners and their teams access information to help them care more effectively for their patients at home?
Which
cancer patients die at home?: the effects of social deprivation and patient
characteristics in England (Project ref: NCP/Y04)
Professor Irene Higginson, Kings College London
Completed: 28 February 1997 Total
cost: £48,057
Meeting
the needs of cancer patients who wish to remain at home until they die: A
systematic review of preferences, problems and cost-effective solutions
(Project ref: NCP/ICV/014/Y)
Professor Irene Higginson, Kings College London
Completed: 31 March 1997 Total
cost: £31,192
Please note:
Copies of the final report are freely available for those projects where the 'total cost' is provided. To receive a copy, please contact us giving details of the project or projects in which you are interested and your full postal address.
Page maintained by Helen Bailey
Last updated 06 June 2008
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