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Scientific
Program
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Monday
September 15th
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10.30 onwards registration and coffee.
Buffet lunch 12.30-1.30pm
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2.00pm
Opening Ceremony
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Welcome to the University of Exeter, Deputy VC.
Welcome from Prof. Littlechild
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2.30pm
Origins of Life on Earth and the Cosmos
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Prof.
Tim Naylor,
University of Exeter, UK
Finding
extra-terrestrial sites for thermophiles.
3.05pm
Prof. David Saul and Charis Shepher, University of Auckland,
NZ
Using SSU rRNA secondary structure to redraw and re-root
the tree of life and to test the hypothesis of a hyperthermophilic
Cenancestor.
3.40pm
Prof.
David Schwartzman, Howard University, Washington,USA and
Prof. Lineweaver, University of New South Wales, Australia.
The hyperthermophilic origin of life revisited.
4.15pm
Devon cream Tea
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4.35pm
Dr.
Alakendra N. Roychoudhury, Geological Sciences, University
of Cape Town,South Africa.
Sulfate Metabolism Across a Thermal Gradient.
5.00pm
Prof. Tairo Oshima, Tokyo University of Pharmacy and Life
Science, Japan
Stability of nucleic acids in the presence of unique polyamines
produced by thermophiles
5.35pm
finish
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6.30pm
Welcoming reception
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Reed Hall, University of Exeter
Welcome by Mayor of Exeter
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Tuesday
September 16th
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9.00am The genome
and its expression
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Session
1. Genome sequencing,annotation and comparative sequence analyses
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Prof.
Mike Adams, University of Athens, Georgia, USA
Chair
- 5 minutes introduction
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9.05am
Dr Hans-Peter Klenk, Electronic Gene Ltd., Germany
Phylogenomics of thermophilic archaea and bacteria
9.35am
Dr. Lanming Chen, University of Copenhagen, Denmark
The complete genome sequences from Sulfolobus acidocaldarius
and Hyperthermus butylicus.
10.05am
Prof. Daniel Prieur, University of Bretagne Occidentale,
Brest, France
Genetic elements of Thermococcales
10.35am
Prof. Wolfgang Liebl et al., Georg-August-University,
Goettingen and Technical University Hamburg-Harburg, Germany
Analysis of the Genome Sequence of the Thermoacidophilic
archaeon Picrophilus torridus.
10.50am
Coffee / Industrial Exhibition
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Session
2. Structural and Functional genomics
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Prof. Tairo
Oshima, Tokyo University of Pharmacy and Life Science, Japan
Chair
- 5 minutes introduction
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11.10am
Prof. Mike Adams, University of Georgia, USA
Structural and Functional Genomics of Pyrococcus furiosus.
11.45am
Prof. Robert Kelly, NCSU Biotechnology Program, Raleigh,
NC, USA
Functional Genomics Approaches for Examining the Microbial
Ecology of
Hyperthermophilic Microorganisms
12.20pm
Dr. Bharat Patel and Dr. Swaminathan, Griffith University,
Brisban, Australia
The anaerobic thermohalophile Halorthermothrix orenii: Phylogeny,
genome plasticity and amylase crystal structures
12.55pm Buffet
Lunch / Commercial Exhibition
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1.55pm
Biodiversity,
phylogeny and physiology
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Session
1. Novel microorganisms
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Prof Karl
Stetter, University of Regensburg, Germany
Chair
- 5 minutes introduction
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2.00pm
Prof. Hugh Morgan,
University
of Waikato, NZ
Colonisation of surfaces in New Zealand thermal springs
2.30pm
Prof. Juergen Wiegel,
University Georgia, USA
Diversity of aerobic and anaerobic alkali-thermophiles
3.00pm
Dr.Reinhard Rachel,
University of Regensburg, Germany
Ignicoccus
and Nanoarchaeum - two hyperthermophilic archaea
living together: Cell Envelope Ultrastructure and possible modes
of interaction
3.30pm
Dr.
David Prangishvili et al., University of Regensberg,
Germany and Copenhagen University, Denmark.
Exceptionally
Diverse Morphotypes and Genomes of Crenarcaeal hyperthermophilic
viruses
3.50pm
Thahira
Rahman et al., University of Ulster, Northern Ireland.
Distribution
and Molecular Characterisation of highly thermophilic bacteria
in cool soil environments.
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5.10pm
Session 2. Applications
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Prof. Juergen
Wiegel, University of Georgia, USA
Chair
- 5 minutes introduction
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5.15pm
Prof. Hilary Lappin-Scott, University of Exeter, UK
Hot, anaerobic biofilms in the surface environment.
5.45pm
Dr. Geoff McMullan, University of Ulster, Northern Ireland
Molecular analysis of Geobacillus isolates- Highly thermophilic
bacteria isolated from cool soil environments
6.10pm
Dr. Gillian Baker, University of Western Cape, South Africa
16S rDNA primers and the unbiased assessment of thermophile
diversity
6.35pm
Prof. Quixin She, Danish Archaea Centre, Copenhagen, Denmark
Studying the dynamic interactions of the conjugative Sulfolobus
pNOB8 with host chromosomes and the implications for horizontal
gene transfer
7.00pm
Prof. Roy Daniel, University of Waikato, NZ.
Thermostability, thermoactivity and True temperature optima.
A third thermal parameter for enzymes
7.30pm
finish Round table discussion / speaker SWRDA and wine
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Wednesday
September 17th
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9.00am
Macromolecular structure/function relationships
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Session
1 DNA replication and repair, cell division, cell cycle control.
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Prof. Mose
Rossi, University of Naples, Italy.
Chair
- 5 minutes introduction
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9.05am
Prof. John Reeve, Ohio State University, USA
Structure-dependent DNA Binding and Compaction of Archaeal
Histones
9.35am
Dr. Mariarita De Felice,Institute of Protein Biochemistry,
CNR, Naples, Italy
Biochemical characterisation of a CDC6-like protein from
Sulfolobus solfataricus
10.05am
Prof. Hannu Myllykallio, University of Paris-Sud, France
Two Distinct pathways for thymidylate (dTMP) synthesis in
hyperthermophilic bacteria
10.35am
Dr. Malcolm White, University of St. Andrews, UK
Archaeal Nucleotide Excision repair: proteins and patches
11.05am
Coffee / Commercial Exhibition
11.20am
Dr. Maria Ciaramella, Institute of Protein Biochemistry,
CNR, Naples, Italy
DNA damage response in Sulfolobus solfataricus.
11.50pm
Dr. James Chong, University of Bath, UK
DNA replication in the thermophiles
12.20pm
Dr. Georg Lipps, University of Bayreuth, Germany
Characterisation of the first member of the DNA-Polymerase
family E: The replication protein of Sulfolobus islandicus plasmid
pRN1
12.50pm
Dr. Yulong Shen et al., Institute of Advanced Science
and Technology, Tsukuba, Japan
Subunit interaction and regulation of activity through the
terminal domains of the family D.DNA Polymerase from Pyrococcus
horikoshii
1.20pm
Dr. Sigridur Hjorleifsdottir,Prokaria Ltd.,Iceland
Novel DNA polymerase genes obtained from complex biomass
using genemining
1.50pm
Packed Lunch and photograph
Afternoon free and Touristic
Trip approx. 2.00pm
departure
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Thursday
September 18th
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9.00am
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Session
2. Thermophilic Proteins
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Prof. David
Rice, University of Sheffield, UK
Chair
- 5 minutes introduction
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9.05am
Dr. Francine Perler, New England Biolabs, MA, USA
Protein Splicing- Lessons from Thermophiles
9.35am
Prof. Frank Robb, University of Maryland, USA
Structural and Functional Analysis of the small heat shock
proteins from hyperthermophiles
10.05pm
Prof. Mike Danson, University of Bath, UK
The 2-oxoacid dehydrogenase multienzyme complexes in the
Archaea.
10.35am
Coffee / Industrial Exhibition
11.05am
Prof. Jenny Littlechild, University of Exeter, UK
Hyperthermophilic dehydrogenase enzymes
11.35am
Prof. Garry Taylor, University of St Andrews, UK
KDG aldolase from Sulfolobus solfataricus
12.05pm
Dr. Esben Lorentzen , European Molecular Biology Laboratories,
Hamburg, Germany
Crystal structure of an archaeal class 1 aldolase reveals
homology to the eukaryotic class 1 aldolases
12.35pm
Dr. Patrick Baker, University of Sheffield, UK
From hyperthermophiles to psychrophiles: the structural basis
of temperature stability of the amino acid dehydrogenases
1.05pm
Dr. Thomas Hansen, Institut Allgemeine Mikrobiologie, Kiel,
Germany
Phosphoglucose Isomerases in Hyperthermophilic Archaea
1.25pm
Buffet Lunch / Industrial Exhibition
Session
2. Thermophilic Proteins (continued)
Prof.
J. Littlechild, University of Exeter; Dr. David Hough, University
of Bath
Chair
2.25pm
Dr. Satya Singh et al., Saurashtra University,
Rajkot, India and National Food Research Institute, Tsukuba,
Japan
Structure and Function Analysis of b-Glucosidase from Thermotoga
maritima, a thermophilic bacteria through Gene Shuffling
2.45pm
Dr. Seigo Shima et al., Max-Planck Institut,
Germany
Hyperthermophilic and Salt-Dependebt Enzymes from Methanopyrus
kandleri
3.05pm
Dr. Anwar Sunna, Potsdam University, Germany
High Resolution Crystal Structure of Caldicellulosiruptor
Carbonhydrate-Binding Module CBM27-1 in Complex with Mannohexaose.
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4.25pm
Industrial Applications
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Session
1.
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Prof. Jakob
Kristjansson, Prokaria, Iceland
Chair
- 5 minutes introduction
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4.30pm
Dr. Chris du Plessis, BHP Billiton, South Africa
Oxygen and Carbon dioxide kinetic challenges for thermophilic
mineral bioleaching processes
5.00pm
Dr. Valentina Umrania , Department of Microbiology, Rajkot,
India
Bioadsorption of heavy metals by thermoacidophilic autotrophs
5.20pm
Prof. Jakob Kristjansson, Prokaria, Iceland
Novel nucleic acid processing enzymes from Thermophilic bacteriophages.
5.50pm
Prof. Tulasi Satyanarayana, University of Dehli, India
Development of an ideal starch saccharification process using
the thermostable amylolytic enzymes of thermophiles.
6.20pm
Industrial Workshop and Wine Reception
7.30 for 8.00pm
Conference Dinner , Great Hall,
University of Exeter
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Friday
September 19th
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9.00am
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Session
2.
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Prof. Garo
Antranikian, Hamburg Technical University, Germany
Chair
- 5 minutes introduction
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9.05am
Dr.
Marc van der Maarel, Centre for Carbohydrate Bioengineering,
Netherlands
Exploring and Exploiting Starch-Modifying Amylomaltases from
Thermophiles
9.35am
Dr. Sanjeev Kumar , University of Dehli, India
Production, purification and enzyme kinetics of a raw strach
hydrolysing thermostable and neutral glucoamylase of Thermomucor
indicae-seudaticae
9.55am
Dr. Slawomir Dabrowski, BioCentrum, University of Denmark
Recombinant Thermostable AP exonuclease from Thermoanerobacter
tengcongenesis tengcongenesis: Cloning, Expression, Purification,
Properties and PCR Application
10.15am
Prof. Brigitte Ahring, Denmark Technical University, Denmark.
Thermophilic ethanol production
10.45am
Coffee / Industrial Exhibition
11.15am
Dr. Ian Taylor, Chirotech Ltd., UK
Applications of thermophilic enzymes in commercial biotransformation
processes
11.45am
Prof Peter Bergquist, Macquarie University, Sydney, Australia
Production of recombinant enzymes from thermophilic microorganisms
in fungal hosts
12.15pm
Prof. Don Cowan, University of Western Cape, South
Africa
Metagenomics, Gene Discovery and the 'Ideal Biocatalyst'
12.45pm
Buffet Lunch
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1.45pm
Macromolecular structure/function relationships
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Session
3. Temperature related effects on metabolism
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Prof. Richard
Sharp,CAMR, Porton Down, UK
Chair
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1.45pm
Dr. Tina Siebers, University of Essen, Germany
EMP and ED pathway in Thermoproteus tenax; Metabolic
parallelism or specific adaptation
2.15pm
Prof. Reinhard Hensel, University of Essen, Germany
Triosephosphate isomerase of the hyperthermophile Thermoproteus
tenax:
Thermostability is not everything
2.45pm
Dr. Jan Massant et al., University of Brussel, Belgium
Metabolic channeling of Carbamoyl Phosphate, a thermolabile
intermediate: evidence for physical interaction between Ckase
and Otase from the hyperthermophile Pyrococcus furiosus
3.05pm
Dr. Danny Charlier, University of Brussel, Belgium
Arginine regulation in Thermotoga neapolitana and T. maritima
3.25am
Prof. Michael Thomm, University of Regensburg, Germany
Regulation of transcription in Pyrococcus
3.55pm
Closing Ceremony
Tea and Departure
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