Ryan Ames
Research Fellow
Wellcome Trust Centre for Biomedical Modelling and Analysis
University of Exeter

Research Themes

My research focuses on using network approaches to study how phenotype arises from complex systems. Currently, I am using these approaches to study the evolution of pathogenicity in yeast in order to identify novel disease-associated pathways.

Computational Biology

My research uses computational approaches to gather, integrate and analyse biological big data, including working extensively with next-generation sequencing data. I make use of existing computational biology techniques and develop novel methods where needed.

Yeast Biology

Many yeast species are important human pathogens that cause recurrent treatable infections and life-threatening illness. My research includes studying the evolution of pathogenicity and the identification of disease-causing genes that could be targeted for treatment of infections.

Centre for Biomedical Modelling and Analysis

A large part of my research within the CBMA involves working on a variety of biomedical projects. These projects include studying diabetes, epigenetic studies in mental illness and muscle degeneration in ageing.

Project Areas

I am involved in multiple projects at the University of Exeter. This secton highlights a few onging projects.

Candida albicans

Identifying disease pathways in the pathogenic yeast Candida albicans

Evolution of pathogenicity

Inferring the evolutionary events that led to pathogenicity in yeast

Medical projects

A variety of collaborations within the CBMA.


Ryan Ames

Wellcome Trust Centre for Biomedical Modelling and Analysis

University of Exeter

RILD Level 3