- 2009 Associate of the High Education Academy
- 1999 Ph.D. in Chemistry, SCL, University of Basel, Basel, Switzerland
- 1993 M.S. in Chemistry, Novosibirsk State University, Novosibirsk, Russia
- 2006-present Research Fellow, School of Biosciences, University of Exeter, UK.
- 2004-06 Research Associate, Department of Chemistry, University of Cambridge, UK.
- 2002-04 Research Associate, Département de Chimie, Université de Fribourg, Switzerland.
- 2000-02 Research Fellow, School of Chemistry, University of Birmingham, UK.
Gold nanoparticles synthesis
Nanoparticle-based biosensors have been suggested as a possible alternative to continuous-gold surface plasmon resonance sensors. The strong optical extinction in the visible region of the electromagnetic spectrum exhibited by noble metal nanoparticles arises when the incident photon frequency is in resonance with a localised surface plasmon mode in the conduction band of the nanoparticles.
The optical extinction has a contribution from both scatter and absorption with scattering dominating when spherical particles have a diameter greater than approximately 25 nm. The optical properties of the nanoparticles depend on their composition, shape, and size and therefore they may be tuned and optimised for a given application by nanoparticle-farication methods.
Label-free biospecific photonic array sensors
Microarray biosensor platform is developed which is based on optical scattering properties of gold nanoparticles that have been synthesised in situ on the substrate surface. When the sensor array is functionalised with various biomolecules it allows detection of specific biomarkers in analyte samples using real time kinetic data.
Evanescent CRD LSPR spectroscopy
Molecular level interaction at the interfaces including biological events such as protein adsorption to the surface and protein-antibody binding can been observed by monitoring the change in the extinction of the metal nanoparticle using a number of techniques including evanescent wave cavity ring-down spectroscopy (eCRDS).